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Enrichment——What, Why, How· Environmental enrichment has been variously defined, but generally includes the goal of improving the welfare of the animal through the thoughtful inclusion of meaningful features to the cage environment.· In some cases, the objective of enrichment is to increase the expression of certain behaviors, while in other cases reduction of specific behaviors is intended.· In all instances, the provision of enrichment should neither negatively impact the health and safety of the animal, nor its utility for research.Enrichment--What, Why, How · Enrichment is typically intended to improve animal welfare over some established baseline.· Often, the wild counterpart of the laboratory animal is held up as the standard for comparison.· However, this comparison may be inadequate due to the potential for changes to have occurred in the biology of the laboratory animal (e.g., mouse) following generations of targeted breeding.· The question thus becomes what standard should be used as the benchmark for mouse well-being.