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Water-soluble fullerenes C60[N(CH2)2OH]12, C60[N(CH2)2NH2]10, and C60[N(CH2)2COOH]10,were synthesized by improved nitrene chemistry[1].C60 was reacted with azide small molecules (N3(CH2)2OH, N3(CH2)2NH2 and N3(CH2)2COOH) to produce multi-adducted derivatives,C60[N(CH2)2OH]12, C60[N(CH2)2NH2]10, and C60[N(CH2)2COOH]10.