Gold Catalyzed Chemo-and Site-Selective C-H Functionalization

• 作 者: YuZhunzhun;LiuYuan;MaBen;XiaFei;LiuLu;ZhangJunliang;
• 机 构: Shanghai Key Laboratory of Green Chemistry and Chemical Processes,Department of Chemistry,East China
• 出 处: 中国化学会全国第十二届有机合成化学学术研讨会
• 发表日期: 2015年期

　　In last few years,gold revealed more and more unique properties in carbene chemistry.Last year,we disclosed that the gold carbenes have an unprecedented chemo-and site-selectivity and ligand effect toward the functionalization of C-H bond of phenol.1 Although Shi and co-workers2 analyzed the electronic structures of gold carbenes by using the Density Functional Theory(DFT)calculations,no comprehensive mechanistic insight on the overall pathways of aromatic C(sp2)-H insertion with carbene has been provided so far.