【摘 要】
:
Treatment options for early-stage prostate cancer are well defined, and localized prostate cancer can be cured by several therapeutic strategies.However, the outcome is still disappointing in advanced
【机 构】
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SHIMA Institution for Quantum Medicine Japan
【出 处】
:
BITs 3rd Annual World Cancer Congress-2012(2012第五届世界癌症大会)
论文部分内容阅读
Treatment options for early-stage prostate cancer are well defined, and localized prostate cancer can be cured by several therapeutic strategies.However, the outcome is still disappointing in advanced prostate cancer.A variety of chemotherapeutic approaches, including docetaxel, have been tried to control hormone-refractory prostate cancer,but none are yet fully satisfactory in terms of complete cure, with the least number of side effects.An effective new modality for the treatment of hormone refractory prostate cancer is urgently needed.We introduce a new effective method to control hormone refractory prostate cancer cells by using a far-infrared ray (FIR) emitter.The growth of three human prostate cancer cell lines (Du145, PC-3 and LNCaP) was suppressed in vitro and vivo by FIR.G1 arrest and apoptotic pathway proteins were induced by FIR with intensified expressions of apoptosis-related mRNA on cDNA microarray.We analyzed FIR that were effective on cancer control, and found that incoherent terahertz ray shorter than that of 10 micron meter work on this effect against prostate cancer.
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