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Previous studies have found reduced responses to acute stressor due to repeated or prolonged exposure to background stress.However,the neural mechanism underlying the impact of mild background stress on acute stress reactivity in health individuals has not yet been elucidated.To examine the role of stress neurocircuit especially the hippocampus in habituation to stress,the current study measured the number of daily life stress events that have occurred during the past 24 hours as the index of background stress in 48 young healthy individuals.