Precisely Functionalized Molecular Nanoparticles Are Unique Elements for Macromolecular Science: Fro

• 作 者: Stephen Z. D. Cheng
• 机 构: Department of Polymer Science,College of Polymer Science and Polymer Engineering,The University of A
• 出 处: 2014 年两岸三地高分子液晶态与超分子有序结构学术研讨会暨第十三届全国高分子液晶态与超分子有序结构学术论文报告会
• 发表日期: 2014年1期

We present a unique approach to the design and synthesis of "giant molecules" based on "nano-atoms" for engineering structures across multiple length scales and controlling their macroscopic properties.Herein,"nano-atoms" refer to shape-persistent molecular nanoparticles (MNPs) with precisely-defined chemical structures and surface functionalities that can serve as elemental building blocks for the precision synthesis of "giant molecules" by methods such as sequential click approach.Typical "nano-atoms" include those MNPs based on fullerenes,polyhedral oligomericsilsesquioxanes,polyoxometalates,and folded globular proteins.The resulting "giant molecules" are precisely-defined macromolecules.They include,but are not limited to,giant surfactants,giant shape amphiphiles,and giant polyhedra.Giant surfactants are polymer tail-tethered "nano-atoms" where the two components have drastic chemical differences to impart amphiphilicity.Giant shape amphiphiles are built up by covalently-bonded MNPs of distinct shapes where the self-assembly is not only driven by chemical interactions but are also largely influenced by the packing constraints of each individual shape.Giant polyhedra are either made of a large MNP or by deliberately placing "nano-atoms" at the vertices of a polyhedron.In general,giant molecules capture the essential structural features of their small-molecule counterparts in many ways but possess much larger sizes.