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  5. Bioorthogonal Identification of GST Substrates (BIGS) with Engineered GST Enzymes and Matched Glutat

Bioorthogonal Identification of GST Substrates (BIGS) with Engineered GST Enzymes and Matched Glutat

来源 :第八届中国蛋白质组学大会 | 被引量 : 0次 | 上传用户：shengweizheng
【摘 要】
：
Glutathione S-transferase (GST) is one of the most critical enzymes for the purpose of detoxification during drug metabolism.GST can reversibly catalyze the conjugation of the reduced form of glutathi
【作 者】
：
Shan Feng Lei Zhang Gulishana Adilijiang Jieyuan Liu Yiyi Gong Lixiao Gu Qi Zhang Zhenyu Zhang Haiteng Deng 
【机 构】
：
MOE Key Laboratory of Bioinformatics,School of Life Sciences,Tsinghua University,Beijing,China,10008
【出 处】
：
第八届中国蛋白质组学大会
【发表日期】
：
2013年11期
【关键词】
：
Glutathione S-transferase Glutathione analogues GST mutants BIGS 
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Glutathione S-transferase (GST) is one of the most critical enzymes for the purpose of detoxification during drug metabolism.GST can reversibly catalyze the conjugation of the reduced form of glutathione (GSH) to a wide range of xenobiotic substrates.
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