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The biological effects was assumed to be diverse induced by low dose radiation of 0.5 Gy and lowers.Previously, we have transcriptional profiling of human lyphoblastoid cells after difference γ-rays doses including the low doses 0.05, 0.2 and 0.5 Gy.The p53-inducible gene 3 (PIG3) is one of these inducible genes by low dose radiation.