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Methods. Non-inteiventional studies evaluating the predictors for mortality of elderly population with CSI were searched in Medline, Embase, Sciencedirect and OVID database (all to May 2012). Only observational studies with eligible data were included. Quality of included studies were assessed by a modified quality assessment tool, which previously designed for observational study. The effects of studies~combined with the study quality score using a model of best-evidence synthesis.