【摘 要】
：
Availability of the genome sequences of several organisms has opened up an enormous opportunity for researchers all over the world to study and identify pro
【机 构】
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Laboratory of Molecular Biology National Cancer Institute Bethesda, MD USA
【出 处】
：
BIT‘s2nd Annual World Cancer Congess-2009 (2009第二届癌症大会)
论文部分内容阅读
Availability of the genome sequences of several organisms has opened up an enormous opportunity for researchers all over the world to study and identify protein and other therapeutic targets for a wide range of diseases, including cancer.The Human Genome Project (HGP), that includes the expressed sequence tag (EST) database and the genome sequence database, provides detailed information about the structure, organization and function of the identified human genes.Our laboratory is interested in developing antibody-based targeted therapies for the treatment of cancer.Ideal targets for the irnmuno-based therapy of cancers are proteins that are expressed on cancer cells at high levels but are not expressed in any essential normal tissues like the heart, brain, liver, kidney, etc.The target proteins must also be located on the cell surface, where they would be accessible to antibodies or antibody-based therapeutics.
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