Overexpression of AIB1 in Papillary Thyroid Carcinoma Positively Correlates with Lymph Node Metastas

• 作 者: Mu-YuanLiu[1]Hai-PengGuo[1]Chao-QunHong[2]Han-WeiPeng[1]Xi-HongYang[1]HaoZhang[2]
• 机 构: From Head and Neck Department,Cancer Hospital,Shantou University,Shantou,515000,China
• 出 处: 2012医学科学前沿暨第二届个体化治疗与抗肿瘤药物研究新趋向研讨会
• 发表日期: 2012年期

　　Background:AIB1,a new oncogenic coactivator,is commonly overexpressed and amplified in variety of human cancers.The status of AIB1 expression in papillary thyroid carcinoma (PTC) and its clinical significance are unclear.Methods:in this study,AIB1 expression in PTC was examined by immunohistochemistry using tissue microarrays comprised of 90 PTC specimens and 20 normal thyroid tissue specimens.