Sequential Probability Ratio Tests in Medical Product Safety Evaluation

来源 :泛华统计学会(icsa)2015年学术会议 | 被引量 : 0次 | 上传用户：gujianjia

【摘要】

：

Sequential probability ratio test(SPRT) and its variants have recently received much attention in safety evaluation due to its some well-known merits,e.g.,minim

【作者】

：

Jie Chen

【机构】

：

Novartis

【出处】

：

泛华统计学会(icsa)2015年学术会议

【发表日期】

：

2015年7期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

Sequential probability ratio test(SPRT) and its variants have recently received much attention in safety evaluation due to its some well-known merits,e.g.,minimum expected sample size,full sequential testing feature,etc.

其他文献

Selection of latent variables for multiple mixed-outcome models

Latent variable models have been widely used for modeling the dependence structure of multiple outcomes data.As the information of a latent variable model is of

会议

Sure Screening by Ranking the Canonical Correlations

The sure independence screening procedure by ranking the marginal Pearson correlation is well documented in literatures and works satisfactorily in the ultra-hi

会议

Missing data and estimation-Simulation results of comparing imputation methods

For chronic diseases like psoriasis,the evaluation of long-term effects are important for physicians and patients with respect to treatment decisions.In long-te

会议

Analysis of Proportional Mean Residual Life Model with Latent Variables

Mean residual life model is often employed to study the expected remaining life times.In this article,we propose a proportional mean residual life model with la

会议

Robust estimation and model selection with nonignorable nonresponse

All existing methods handling nonignorable missing data reply on the correct specification of some parametric models which are very difficult to check.

会议

ROC for incident disease using multivariate markers with nonrandom dropout

Although variance is usually dealt as a nuisance in many classical statistical analyses,it has received increasing attention as an interest of its own in many f

会议

Intrinsic random functions and universal kriging on the circle

Intrinsic random functions(IRF) provide a versatile approach when the assumption of second-order stationarity is not met.Here,we develop the IRF theory on the c

会议

A semiparametrically efficient estimator of the time-varying effects for survival data with time-dep

会议

Statistical Methods for Studying Disease Etiologic Heterogeneity

A fundamental goal of epidemiologic research is to investigate the relationship between exposures and disease risk.Cases of the disease are often considered a s

会议

Power Calculations for the Stepped Wedge Designs

Background:The stepped wedge design(SWD) provides a rigorous,randomized scheme for evaluation of interventions.One example is the assessment of early ART access

会议

Sequential Probability Ratio Tests in Medical Product Safety Evaluation

其他学术论文