Critical-size bone defects are among the more difficult regenerative therapies to successfully achieve.The implantation of engineered constructs obtained by seeding osteogenic cells, such as Mesenchym
During the past two decades, research on ceramic scaffolds for bone regeneration has progressed rapidly;however, currently available porous scaffolds remain unsuitable for load-bearing applications.
Phosphate based glasses are a unique group of materials in that they are degradable and also the rate of degradation may be altered over several orders of magnitude by simply altering the glass compos
Introduction Pelvic organ prolapse (POP) is the herniation of the pelvic organs into the vagina.Current support meshes lead to problems of wall erosion and poor integration, partly due to inferior mec
We have used both mesenchymal stem cells (MSC)andinduced pluripotent stem cells (iPSC)as sources of human cardiomyocytesto grow vascularised cardiac tissue in chambers in vivo.
Cell transplantation is a promising approach for patients with myocardial infarction.However, following injection, retention of the transplanted cells in the injected area remains a central issue, whi
Recent advances in the field of tissue engineering and regenerative medicine have offered new therapeutic opportunities for repairing damaged tissues and organs.
Nanoconductive materials have emerged as one of the most interesting and promising candidate biomaterials for engineered cardiac tissue (ECTs) applications.
Heart failure is a major international health issue.Myocardial mass loss and lack of contractility are precursors to heart failure.Surgical demand for effective myocardial repair is tempered by a pauc
Even after dec ades of implantationprosthetic vascular grafts remain largely without an endothelium in humans.While thisshortcoming does not affect the clinical performance of large bore prostheses, i