Low SOX17 expression diagnostic and prognostic significance in de novo acute myeloid leukemia with n

来源 :The 35th World Congress of the International Society of Hema | 被引量 : 0次 | 上传用户：peng23

【摘要】

：

Objective Aberrant expression of SRY-box containing gene 17 (SOX17) has been observed in several solid tumors.However,little is known about SOX17 expression in acute myeloid leukemia(AML).The purpose

【作者】

：

Chun-yan Tang Jiang Lin Wei Qian Jing Yang Ji-chun Ma Zhao-qun Deng Lei Yang Cui An Xiang-mei Wen Ying-ying Zhang Jun Qian

【机构】

：

Affiliated People's Hospital of Jiangsu University

【出处】

：

The 35th World Congress of the International Society of Hema

【发表日期】

：

2014年5期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

Objective Aberrant expression of SRY-box containing gene 17 (SOX17) has been observed in several solid tumors.However,little is known about SOX17 expression in acute myeloid leukemia(AML).The purpose of this study was to investigate the alterations of SOX17 expression and to explore its clinical significance in AML.

其他文献

CEBPA gene mutations in Chinese patients with intermediate cytogenetic risk profile acute myeloid le

Objective To investigate CCAAT/enhancer binding protein alpha (CEBPA) gene mutations in acute myeloid leukemia (AML) patients with intermediate-risk cytogenetics.Methods Mutation analysis of the entir

会议

The Expression level of HLS5 is correlated with the Clinical Outcomes of acute lymphoid leukemia (AL

Background HLS5 belongs to the RBCC (Ring-finger,B-box,coiled-coil) family,a family of tumor suppressive genes including Pm,Tif1-α,Herf and Rfp,it has been reported to regulate erythroid differentiati

会议

ROLE OF INDUCTION AND CONSOLIDATION CHEMOTHERAPY IN ELDERLY ACUTE MYELOID LEUKEMIA

Background Diagnosis of acute myeloid leukemia (AML) at an elderly age generally predicts poor clinical outcomes.Elderly acute myeloid leukemia (AML) patients usually have a bad prognosis.Because the

会议

Immunophenotype of NK cells in patients from Mexican patients with acute myeloid leukemia. Prelimina

Introduction Natural killer (NK) cells are an important part of the organisms innate immune system.They can destroy virally infected and malignant cells without prior sensitization.These cells recogni

会议

Standard induction followed by low dose cytarabine for the treatment of acute myeloid leukemia of Do

Objective Although acute myeloid leukemia occurring in patients with Down syndrome (AML-DS)is generally chemosensitive,those patients are more susceptible to regimen-related toxicities,and the optimal

会议

SNP analyses in cytarabine metabolizing enzymes in AML patients and their impact on treatment respon

Objective Cytosine arabinoside (Ara-C) is widely used to treat acute myeloid leukemia (AML) and Ara-C metabolizing enzymes could affect the cytotoxicity of Ara-C.To assess the pharmacogenomic effects

会议

The clinical efficacy of the patients of acute myeloid leukemia and myelodysplastic syndromes treate

Objective To observe the clinical safety and efficacy of decitabine in patients of acute myeloid leukemia and myelodysplastic syndromes.Methods Totally 79 patients with MDS/AML were divided into three

会议

Study of the methylation level in vivo of the patients of myelodysplastic syndrome and acute myeloid

Objective To detect the level of MDS / AML patients treated with decitabine and study the relationship between the level of DNA methylation in the tumor cells of MDS / AML and decitabine.To discuss th

会议

High Prognostic Value of Minimal Residual Disease Detected by Flow Cytometry-Enhanced Fluorescence i

Background Acute myeloid leukemia (AML) is generally regarded as a disorder of stem cells,known as leukemic initiating cells (LICs),which initiate the disease and contribute to relapses.Although the p

会议

FISH+CD34+CD38-cells detected in newly diagnosed acute myeloid leukemia patients can predict the cli

Background In acute myeloid leukemia (AML),the leukemia initiating cells (LICs) or leukemia stem cells (LSCs) is found within the CD34+CD38- cell compartment.The LICs subpopulation survives chemothera

会议

Low SOX17 expression diagnostic and prognostic significance in de novo acute myeloid leukemia with n

其他学术论文