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Anti-HBV vaccine was found to prevent some liver tumors as well as anti-HPV vaccine is able to prevent most of the cervical cancers.TAA were studies in SV40 and Polyoma viruses that were partners for there stransfer to human cancer.Cancer immunotherapy, or the manipulation of the naturally occurring oncolytic immune reaction, is based on the observation that both in animals and humans neoplastic cell antigens stimulate the onset of specific humoral and cellular antibodies.