芪参益气方抗心肌纤维化效应的差异性研究

来源 :第17届中国南方国际心血管病学术会议 | 被引量 : 0次 | 上传用户：Daemonman

【摘要】

：

目的观察在不同类型心肌纤维化、不同干预时程中,芪参益气方抗心肌纤维化的效应及其差异性.方法将大鼠随机分为对照组、模型组、缬沙坦组、芪参益气组,采用腹主动脉缩窄建立反应性心肌纤维化模型、注射心肌肌球蛋白建立修复性心肌纤维化模型,分别于给药4周、8周后取材,称量大鼠体重、心脏质量、左心室质量;行心肌HE和Masson染色;碱水解法检测心肌羟脯氨酸含量;ELISA检测血清PⅠCP、PⅢNT、CTX-

【作者】

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吕仕超吴美芳李萌王强王晓景徐玲张军平

【机构】

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天津中医药大学第一附属医院天津中医药大学

【出处】

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第17届中国南方国际心血管病学术会议

【发表日期】

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2015年9期

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