Enhanced luminol electrochemiluminescence triggered by an electrode functionalized with dendrimers m

• 作 者: LingShan Gong Guifang Xu Yanyu Lin Ting Yang Yuejin Tong Hong Dai Guonan Chen
• 机 构: College of Chemistry and Chemical engineering ,Fujian Normal University,Fuzhou,Fujian,350108,China
• 出 处: 第八届全国微全分析系统学术会议、第三届全国微纳尺度生物分离分析学术会议暨第五届国际微化学与微系统学术会议
• 发表日期: 2013年2期
• 关键词: Electrochemiluminescence Luminol Poly(amidoamine) dendrimer Titanate nanotubes S

　　Herein,we have constructed a novel electrochemiluminescence (ECL) platform by functionalizing a poly (amidoamine) dendrimer (PAAD) with titanate nanotubes (TiNTs).The PAAD has an open spherical structure that possesses a high density of active groups and thus favors mass transport,while the TiNTs possess excellent electronic conductivity and thus can promote electron transfer on the surface of a glassy carbon electrode (GCE).A study on the intensity and stability of the ECL of luminol on the modified GCE revealed a substantial improvement compared to that of a bare GCE.The effects of the concentration of TiNTs,the pH value of the solution,and of electrochemical parameters on the intensity of the ECL of luminol were studied and resulted in a sensitive ECL sensor for hydrogen peroxide (H2O2) that works in the concentration range of 1 nM to 0.9 μM.The scavenging effect of superoxide dismutase (SOD) on the H2O2 electrode ECL was then exploited to design a biosensor for the determination of SOD in concentrations between 50 and 500 nM.