Chiral diamine ligand is one of the most important ligands in asymmetric catalytic reaction.Among them,the majority is about 1,2-diamine[1] and about 1,4-diamine[2] is rarely seen reports.Enantioselec
Direct cyanation at the α-position of nitrogen-containing heterocycles such as tetrahydroisoquinolines is an attractive method for the formation of α-amino nitriles which are highly versatile because