1,3-氧氮天然生物碱化合物骨架合成研究

来源 :河南省化学会2016年学术年会 | 被引量 : 0次 | 上传用户：lsxfa

【摘要】

：

1,3-氧氮天然生物碱Chinese Bittersweet Alkaloid(1)和(2)是一类具有全新骨架的生物活性化合物[1]。作为生物活性的研究,经过美国NCI癌症研究中心筛选,该类化合物中化合物(2)在筛选的9个细胞系的60个癌细胞株中对非小细胞肺癌HOP-92细胞株展现出良好的抑制活性。

【作者】

：

刘坤王可可尹卫平

【机构】

：

河南科技大学化工与制药学院;河南省伏牛山野生药材基源工程技术中心,洛阳,471023 河南科技大学

【出处】

：

河南省化学会2016年学术年会

【发表日期】

：

2016年10期

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1,3-氧氮天然生物碱化合物骨架合成研究

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