CRISPR-Cas9 Mediated Efficient PD-1 Disruption on Mouse T Cells for Colorectal Cancer Treament in vi

来源 :2016第九届世界癌症大会 | 被引量 : 0次 | 上传用户:atom1999
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  Programmed cell death protein 1/programmed death ligands 1(PD-1/PD-L1) is a critical for modulating immune responses to cancer.A new class of monoclonal antibodies that block PD-1/PD-L1 immune checkpoint signal,activate the immune system to attack tumors and are therefore used with varying success to treat some types of cancer.
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