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  5. MiRNA expression in breast cancer varies with lymph node metastasis and other clinicpathologic featu

MiRNA expression in breast cancer varies with lymph node metastasis and other clinicpathologic featu

来源 :2016乳腺癌诊治新进展学术年会 | 被引量 : 0次 | 上传用户：boaijuan
【摘 要】
：
Background:Breast carcinoma is the most common malignant tumor in females,lymph node status is one of the most important prognostic factors in patients with breast cancer.MiRNAs have been shown to hav
【作 者】
：
郑亚兵 邵喜英 石磊 黄平 黄圆 曹文明 王晓稼 
【机 构】
：
浙江省肿瘤医院乳腺肿瘤内科,浙江,杭州,310022
【出 处】
：
2016乳腺癌诊治新进展学术年会
【发表日期】
：
2016年3期
【关键词】
：
breast cancer microRNAs microarray lymph node metastasis prognosis 
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　　Background:Breast carcinoma is the most common malignant tumor in females,lymph node status is one of the most important prognostic factors in patients with breast cancer.MiRNAs have been shown to have important role in oncogenesis,invasion,and metastasis via epigenetic posttranscriptional gene regulation.However lymphatic metastasis related miRNAs of breast cancer has not been well documented.The aim of this study was to identify and evaluate miRNAs related to breast cancer lymph node metas-tasis,and explore the clinical significance of the differential expressed miRNAs in breast cancer patients.
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