Protein aggregation to form amyloid fibrils is associated with a variety of neurodegenerative diseases,in which oligomeric intermediates formed during the e
A protein can dynamically inter-convert between the predominant ground-state and lowly populated excited-state structures.The dynamic fluctuation among diff
Circulating Tumor Cells(CTCs)have been demonstrated to be excellent biomarkers for cancer diagnosis and prognosis.During the past ten years,tremendous amoun
Many RNA viruses including Simian Retrovirus type 1(SRV-1)utilize minus-one ribosomal frameshifting as an alternative translation mechanism to generate stab
Crystallography is an important method to determine the biological macromolecular structure at atomic resolution,and the crystal diffraction measurement is
Hantaviruses,which belong to the genus Hantavirus in the family Bunyaviridae,infect mammals,including humans,causing either hemorrhagic fever with renal syn
Single-molecule fluorescent spectroscopy can provide unique perspectives which complement conventional bulk biochemical approaches.To illuminate the transmi
A series of surfactant-like peptides are designed and synthesized.Taking advantage of peptides versatile molecular design,six peptides that have the same am