【摘 要】
：
Quinline derivatives are popular therapeutic agents with wide activity range.They are used as antifungal1 and antibacterial2 medicines,drugs intransmissible sP0ngiform encephalophaties (TSE)3,and prog
【机 构】
：
Jagiellonian University,30-060 Kraków, ul.R.Ingardena 3, Poland
【出 处】
：
2006中国天津世界艾滋病日科技会议
论文部分内容阅读
Quinline derivatives are popular therapeutic agents with wide activity range.They are used as antifungal1 and antibacterial2 medicines,drugs intransmissible sP0ngiform encephalophaties (TSE)3,and progesterone receptor modulators4.Styrylquinolines (SQ) are a group of compounds capable of HIV integrase inhibition5.Their important feature is the activity against HIV-1 strains that are resistant to other antiviral compounds6.The docking data with HIV integrase core domain confirm the hypothesis that SQ interact with protein near the DDE triade7.
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