【摘 要】
：
Epigenetic marks,including histone modifications,DNA methylation and histone variants,play a key role in determining transcriptional outcomes.The availabili
【机 构】
：
Department of Bioinformatics,the State Key Laboratory of Plant Physiology and Biochemistry,Institute
【出 处】
：
2014 International Workshop and Summer School on“ Biological
论文部分内容阅读
Epigenetic marks,including histone modifications,DNA methylation and histone variants,play a key role in determining transcriptional outcomes.The availability of the high-throughput sequencing data allows us to characterize the genome-wide distribution patterns of epigenetic marks,which have improved our understanding of the relationship between chromatin modification/structure and genes expression.More and more studies have found that epigenetic mechanisms have been implicated in many biological processes,such as Transposon Element silencing and long-range interactions within the genome.Moreover,those studies have found there are different layers of cross-talk and interplay among epigenetic marks to be involved in chromatindependent processes.Here,we take advantage of evidence from recent genetic,biochemical and highthroughput sequencing studies to explore the complex cross-talk between different epigenetic patterns,and address how these epigenetic marks interplay with each other and then affect gene transcription.Finally,we build a cross-talk network and analyze the characteristic of the network.Comprehensive cross-talk network of epigenetic marks will help in fully understanding the functional roles and biological impact of epigenetic regulation.
其他文献
As we know,anthracene has an intense π-π stacking and interacting tendency owing to its planar structure,enlarged π-conjugation system and a relatively l
Over the last two decades,iridium(Ⅲ)complexes have emerged as efficient phosphorescent materials for OLEDs because of their good stability,high PL quantum
The advantages of tunable energy levels,large absorption coefficients and excellent structural stability owing to thermal and solvent resistance make conjug
目的:随着环境的不断恶化，空气质量越来越差，并且已经严重影响到了人们的身体健康，雾霾已经遍布中国的众多城市，使得呼吸系统疾病的发病率日渐升高。急性肺损伤(ALI)/呼吸窘迫综
Dioxins,by-products of various industrial processes,are commonly regarded as highly toxic compounds that are environmental pollutants and persistent organic
Compared with green and red OLEDs,it is difficult to obtain deep-blue electroluminescent materials with a CIE coordinate of y
Organic optoelectronic devices,including organic light-emitting devices(OLEDs)and organic solar cells(OSCs)have been attracting considerable interest as nex
通过Stille 偶联反应合成了基于萘酰亚胺和苯并噻二唑的新型共轭聚合物.并对聚合物进行了一系列的结构表征和性能测试,结果表明聚合物的光学能带隙为1.37 eV,电化学能带
Recently,luminescent liquid crystal materials with metal ions(luminescent metallomesogens)are a particularly enticing family due to their outstanding optoel
星间链路、自主定轨和时间同步是 BDS（北斗卫星导航系统）等混合卫星导航星座建设和应用中的重要组成部分。本文紧密结合BDS等混合卫星导航星座的实际，综合运用数学、统计学等理