Specifically targeting human telomeric dimeric G-quadruplexes by polyehter-tethered di-berberine der

来源 :中国化学会第四届卟啉与酞菁学术研讨会 | 被引量 : 0次 | 上传用户：yao2042547

【摘要】

：

　　The design and synthesis of binders specifically multiple G-quadruplex units in the 3-terminal overhang of human telomeric DNA has attracted considerable at

【作者】

：

Zi-Qi Li Ting-Cong Liao Wen-Hua Chen Chun-Qiong Zhou

【机构】

：

GuangdongProvincialKeyLaboratoryofNewDrugScreening,SchoolofPharmaceuticalSciences,SouthernMedicalUni

【出处】

：

中国化学会第四届卟啉与酞菁学术研讨会

【发表日期】

：

2017年7期

【关键词】

：

Di-berberine dimeric quadruplex DNA telomere binding selectivity

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　　The design and synthesis of binders specifically multiple G-quadruplex units in the 3-terminal overhang of human telomeric DNA has attracted considerable attention,which will promote to develop some selective anticancer agents with fewer side effects.

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