BMSCs表达甲状旁腺发育不同阶段基因的研究

来源 :中国生理学会消化内分泌生殖代谢生理专业委员会2014年消化内分泌生殖代谢学术会议 | 被引量 : 0次 | 上传用户：sdzhao

【摘要】

：

甲状旁腺胚胎发育先表达甲状旁腺和胸腺前体细胞的共同转录因子Pax1、Eya1和Six,然后两个腺体分离迁移定位发育,甲状旁腺细胞表达Gcm2、CaSR和PTH.PTH是调节钙磷代谢的主要激素,长期以来认为甲状旁腺是PTH合成和分泌的唯一来源,但近年发现胸腺、下丘脑表达PTH基因,我们以前研究表明骨髓间充质干细胞(BMSCs)可表达PTH,骨髓可能是合成和分泌PTH的另一来源.本研究通过测定BMSC

【作者】

：

邹惟莹杨蓓张大雷吴磊熊明娣赵林彤任敏戴群杜毓菁凌萍朱盛华邹挺

【机构】

：

南昌大学基础医学院,江西南昌,330006 南昌大学第二临床医学院,江西南昌,330006

【出处】

：

中国生理学会消化内分泌生殖代谢生理专业委员会2014年消化内分泌生殖代谢学术会议

【发表日期】

：

2014年8期

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BMSCs表达甲状旁腺发育不同阶段基因的研究

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