In vivo fate and pharmacodynamic evaluation of siRNA loaded novel cationic liposomes on lung cancer

来源 :2015年中国药物制剂大会、中国药学会药剂专业委员会2015年学术年会暨国际控释协会中国分会2015年学术年会 | 被引量 : 0次 | 上传用户：hngscg

【摘要】

：

　　In our study, targeting Anti-EGFR mAb NDOA co-modified cationic liposomes loaded with Survivin-siRNA and MRP1-siRNA (EGFR-PEG-NCLs-siRNA) were formulated, w

【作者】

：

Dan-Feng Shi Pan Shen Qing-Ri Cao Jing-Hao Cui

【机构】

：

College of Pharmaceutical Science, Soochow University, Suzhou, China, 215123

【出处】

：

2015年中国药物制剂大会、中国药学会药剂专业委员会2015年学术年会暨国际控释协会中国分会2015年学术年会

【发表日期】

：

2015年期

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　　In our study, targeting Anti-EGFR mAb NDOA co-modified cationic liposomes loaded with Survivin-siRNA and MRP1-siRNA (EGFR-PEG-NCLs-siRNA) were formulated, with an appropriate particle size, zeta potential and high encapsulation efficiency.

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In vivo fate and pharmacodynamic evaluation of siRNA loaded novel cationic liposomes on lung cancer

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