【摘 要】
：
Aim: Electrochemotherapy is a local treatment that by permeabilizing electric pulses, locally at the site of their application, potentiate cytotoxicity of n
【机 构】
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Head of Melanoma Tumor Board Institute of Oncology Slovenia
【出 处】
：
BIT Life Sciences' 1st Annual World Cancer Congess-2008(
论文部分内容阅读
Aim: Electrochemotherapy is a local treatment that by permeabilizing electric pulses, locally at the site of their application, potentiate cytotoxicity of non-permeant or poorly permeant anticancer drugs, with high intrinsic cytotoxicity, like bleomycin or cisplatin.It is aimed at treatment of cutaneous and subcutaneous tumout nodules of different histology with palliative intent.Results: In clinical studies electrochemotherapy proved to be highly effective.Overall treatment response on various tumours, but predominantly in melanoma, was 85% objective responses, from these 75% complete responses of the treated nodules.Conclusions: The main advantages of electrochemotherapy are its simple application, minimum side effects, the possibility of repetitive treatment with equal effectiveness and effectiveness on tumours emerging in areas that were already treated by surgery or radiotherapy.
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