Human immunodeficiency virus type 1(HIV-1),the pathogen of acquired immunodeficiency syndrome(AIDS),causes about 2 million people to death every year.Fusion
Organophosphorus agents(OPs)like sarin,VX,or soman could inhibit acetylcholinesterase activity and cause poisoning.OPs could bind many proteins,such as buty
Background: Quantitative description of dose-response of a drug for complex systems is essential fortreatment of diseases and drug discovery.Given the growt
Objectives: Drug-resistant Mycobacterium tuberculosis poses a great threat to human health.Tyrosyl-tRNA synthetase(TyrRS)is one of the aminoacyl tRNA synthe
Recent studies have proved that focal adhesion kinase(FAK)is a new potential therapeutic target in cancer therapy.In this study,a virtual scraening was cond
Fullerene and its derivatives show promising prospects for applications in a vast array of biological systems.A key aspect concerning their biomedical appli