Discovery and Identification of Serum Potential Biomarkers for Colorectal Cancer Using TMT Quantitat

• 作 者: Qi Zhang Lingfang Tang Jianguo Ji
• 机 构: StateKeyLaboratoryofProteinandPlantGeneResearch,CollegeofLifeSciences,PekingUniversity,Beijing100871
• 出 处: 第三届全国质谱分析学术报告会
• 发表日期: 2017年12期
• 关键词: Colorectal cancer TMT labeling quantitative proteomics Differentially expressed

　　Colorectal cancer(CRC)is a leading cause of cancer deaths worldwide.Nevertheless,the exact mechanism of CRC occurrence remains unclear,and it is lack of biomarkers for early detection.In this study,we employed a TMT-based quantitative proteomic approach to analyze the proteomic changes in the sera collected from the early staged colorectal cancer patients and healthy volunteers.