A novel ECG analog selectively induces apoptosis of B16-F10 melanoma via activation of autophagy and

来源 :第一届自噬生物学与疾病国际研讨会(The 1st International Symposium on Autophag | 被引量 : 0次 | 上传用户：ronalito

【摘要】

：

【作者】

：

Siyuan Shao Jing Xie Peicheng Zhang

【机构】

：

Department of Pharmacology,Chinese Academy of Medical Sciences,Beijing,China

【出处】

：

第一届自噬生物学与疾病国际研讨会(The 1st International Symposium on Autophag

【发表日期】

：

2015年9期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

Autophagy-induced cancer cell death has become a novel signaling target for development of cancer therapeutic drugs.Green tea polyphenols induced both autophagy and apoptosis in a variety of cancer cells.Here, we synthesized a series of green tea polyphenol analogues among which JP8 was shown to have potent autophagy activation property.

其他文献

A retrospective analysis of 56 recurrent hernia cases received TEP after inguinal hernioplasty with

Objective To explore the feasibility and safety of the laparoscopic totally extraperitoneal prosthesis(TEP) in the treatment of recurrent inguinal hernia after plug perfix mesh repair.Methods 56 TEP c

会议

Recurrent herniaPlug perfix meshTEP

Preparation of volumetric skeletal muscle whole organ acellular matrix to regenerate contractile, va

Introduction Biologic scaffolds prepared from the extracellular matrix (ECM) of acellular mammalian tissues have been confirmed the capability of stimulating restoration of significant muscle mass in

会议

Successfully treated with cook-mesh-repair for diaphragmatic hernia complicated by intestinal obstru

Diaphragmatic hernia is an uncommon complication that can follow transhiatal esophagectomy.We experienced a rare case of diaphragmatic hernia underwent esophagectomy by right thoracic approach on acco

会议

The efficacy of laparoscopic Nissen fundoplication versus anterior 180° partial fundoplication in th

Objective To investigate the High Resolution Manometry results of laparoscopic Nissen fundoplication verse anterior 180° partial fundoplication in the management of hiatal hernia.Methods 110 patients

会议

Laparoscopic Nissen fundoplicationLaparoscopic anterior 180° partial fundoplica

Analysis, prevention and treatment strategies for intraoperative iatrogenic injury of anterior prepe

Objectives To investigate the etiology, prevention and treatment strategies for intraoperative iatrogenic injury of anterior preperitoneal groin hernia repair.Methods A retrospective review of 12 pati

会议

Groin herniaPreperitoneal herniorrhaphyIatrogenic injuryComplication

A comparative experimental study of the influence of different meshes on the structure of vas defere

Objective Explore the influence of heavyweight polypropylene mesh, lightweight polypropylene mesh and polyester mesh on the structure of vas deferens at the different time in rat models.Methods There

会议

HerniaRatMeshVas deferensReproductive functions

Negative pressure wound therapy for mesh-site infection after incisional hernia repair: a case repor

Purpose We reviewed a case of negative pressure wound therapy (NPWT) for mesh-site infection after incisional hernia repair and relevant literature.Methods This was a 76 years old female patient.She h

会议

Negative pressure wound therapyInfected mesh graftIncisional hernia repair

Biologic Mesh versus Synthetic Mesh in Open Inguinal Hernia Repair: System Review and Meta-Analysis

Background Biological meshes are mostly used for abdominal wall reinforcement in infected fields, but no consensus has been reached on its use for inguinal hernia repairing.The purpose of this study w

会议

Biologic meshSynthetic meshOpen inguinal hernia repair

信号衔接蛋白p66Shc的缺失抑制营养缺乏诱导的细胞自噬

失巢凋亡指失去胞外贴附基质而引发的细胞死亡,实体肿瘤细胞耐受失巢凋亡是产生转移的生物学基础之一.细胞自噬是一种高度保守的依赖溶酶体降解受损大分子或细胞器的自我消化过程,从而循环利用降解产物.在实体肿瘤细胞转移过程中,细胞自噬起着不可或缺的作用.p66Shc是信号衔接蛋白ShcA的一个异构体,在正常表皮细胞中高表达,但在转移的非小细胞肺癌细胞中低表达或不表达,临床肺癌组织样品中其表达与患者存活时间负

会议

BMA 155 induces autophagy and following apoptosis associated with NF-κB Pathway in human hepatocarci

Bisindolylmaleimide alkaloid-155 (BMA155) is a synthesized bisindolylmaleimide compound with novel structure.We showed here that BMA155 induced autophagy and following apoptosis associated with NF-κB

会议

A novel ECG analog selectively induces apoptosis of B16-F10 melanoma via activation of autophagy and

其他学术论文