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Pneumatic microvalves involving PDMS elastic membranes [1] have been widely used in many lab-on-chip devices.However,PDMS is highly gas-permeating,less compatible to chemicals and highly absorptive.Fluorinated ethylene propylene (FEP) is chemically-inert,non-adsorptive and air-tight,which is desired for a material to be used for microfluidic chips.