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多胺是由腐胺，精胺和精脒组成的一类带正电的烷基胺类小分子，由精氨酸代谢生成，广泛参与细胞增殖、细胞信号转导和基因表达调控等多种细胞生命活动过程。研究表明，肿瘤细胞快速增殖依赖细胞内的高浓度多胺。
抑制AKt信号通路促进多胺耗竭诱导的A549细胞凋亡
【摘 要】
：
多胺是由腐胺，精胺和精脒组成的一类带正电的烷基胺类小分子，由精氨酸代谢生成，广泛参与细胞增殖、细胞信号转导和基因表达调控等多种细胞生命活动过程。研究表明，肿瘤细胞快速增殖依赖细胞内的高浓度多胺。
【机 构】
：
三峡大学医学院分子生物学研究所 湖北宜昌443002
【出 处】
：
第八届全国医学生物化学与分子生物学、第五届全国临床应用生物化学与分子生物学、2013华东六省一市生物化学与分子生物学联合
【发表日期】
：
2013年2期
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