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Betula platyphylla is a rich repository of pharmacologically active secondary metabolites known as birch triterpenoids(TBP).Here,we cloned the squalene synthase(SS)and squalene epoxidase genetic(SE)sequences from Betula platyphylla that encode the key enzymes that are involved in triterpenoid biosynthesis,and analyzed the conserved domains and phylogenetics of their corresponding proteins.