Zinc significantly changes the aggregation pathway and the structure of aggregates formed by human p

来源 :2013年第四届全国“跨学科蛋白质研究”学术讨论会 | 被引量 : 0次 | 上传用户：yinxiaoyi5858

【摘要】

：

　　Transmissible spongiform encephalopathies (TSEs) are a group of infectious fatal neurodegenerative diseases, and prion protein is the key factor in TSEs.The

【作者】

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潘锴易传伟陈杰梁毅

【机构】

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武汉大学生命科学学院,病毒学国家重点实验室,武汉430072

【出处】

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2013年第四届全国“跨学科蛋白质研究”学术讨论会

【发表日期】

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2013年10期

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　　Transmissible spongiform encephalopathies (TSEs) are a group of infectious fatal neurodegenerative diseases, and prion protein is the key factor in TSEs.The pathological process involves the conversion of normal cellular prion protein (PrPC) into abnormal pathological prion protein (PrpSc).

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Zinc significantly changes the aggregation pathway and the structure of aggregates formed by human p

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