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  5. Electrochemical-assistance for Electron Transfer Dissociation Ion Mobility MS of Peptides and Protei

Electrochemical-assistance for Electron Transfer Dissociation Ion Mobility MS of Peptides and Protei

来源 :第八届中国蛋白质组学大会 | 被引量 : 0次 | 上传用户：kjc
【摘 要】
：
Protein characterization using intact tandem mass spectrometry approaches can be challenged by the presence of disulfide bonds that maintain and stabilize three dimensional structures.Moreover,the pre
【作 者】
：
JP Williams C J.Hughes C Zhou J M.Brown 
【机 构】
：
Waters Corporation,Atlas Park,Manchester,UK M22 5PP
【出 处】
：
第八届中国蛋白质组学大会
【发表日期】
：
2013年11期
【关键词】
：
Ion mobility Electron Transfer Dissociation Intact Proteins Electrochemistry 
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Protein characterization using intact tandem mass spectrometry approaches can be challenged by the presence of disulfide bonds that maintain and stabilize three dimensional structures.Moreover,the presence of multiple disulfide bonds significantly reduces efficiency.
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