Non-synchronic Alteration of Clathrin and PICALM Involved in the Endocytosis in Aβ1-42 Treated Neuro

来源 :2015中国老年医学和老年健康产业大会 | 被引量 : 0次 | 上传用户：pz421769788

【摘要】

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【作者】

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R.Shi Y.Lü

【机构】

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Department of Geriatrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing,

【出处】

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2015中国老年医学和老年健康产业大会

【发表日期】

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2015年7期

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OBJECTIVE: Recent studies have shown that endocytosis involves in the mechanisms of Alzheimers disease (AD).Clathrin and phosphatidylinositol binding clathrin assembly protein (PICALM), as key proteins of clathrin-mediated endocytosis (CME),probably participate in the CME dysfunction in AD development.Hence, the aim of the present study was to investigate the relationship between CME and AD via the alteration of Clathrin and PICALM.

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Non-synchronic Alteration of Clathrin and PICALM Involved in the Endocytosis in Aβ1-42 Treated Neuro

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