Routes to achieving “bright” near-infrared fluorescing nanoparticles: Controlling chromophore aggreg

• 作 者: Stephen H.Foulger
• 机 构: Center for Optical Materials Science and Engineering Technologies Department of Materials Science an
• 出 处: 2nd International congress on advanced materials(AM2013)第二届国
• 发表日期: 2013年12期

　　We present a general approach for the selective imaging of cancer cells using protein activated near-infrared emitting nanoparticles.Poly(propargyl acrylate) (PA) particles with a diameter of 50 nm were surface modified through the copper-catalyzed azide/alkyne cycloaddition of an azide-terminated squaraine dye derivative (az1SQ),a near-infrared emitter,and poly(ethylene glycol) (azPEG) chains.