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  5. Shikonin derivatives as inhibitors of tyrosyl-tRNA synthetasedesign, synthesis and biological evalua

Shikonin derivatives as inhibitors of tyrosyl-tRNA synthetasedesign, synthesis and biological evalua

来源 :第九届国际分子模拟与信息技术应用学术会议(ICMS&I2018) | 被引量 : 0次 | 上传用户：szocean
【摘 要】
：
The development of antibiotics is never a simple stepwise linear process.After numerous setbacks in high-throughput screening and de novo drug design,researcher
【作 者】
：
Han-Yue Qiu Peng-Fei Wang Zi-Zhen Wang Yue-Lin Luo Dong-Qing Hu Jin-Liang Qi Gui-Hua Lu Yan-Jun Pang Rong-Wu Yang Hai-Liang Zhu Xiao-Ming Wang Yong-Hua Yang 
【机 构】
：
StateKeyLaboratoryofPharmaceuticalBiotechnology,NJU-NJFUJointInstituteofPlantMolecularBiology,Nanjin
【出 处】
：
第九届国际分子模拟与信息技术应用学术会议(ICMS&I2018)
【发表日期】
：
2018年5期
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The development of antibiotics is never a simple stepwise linear process.After numerous setbacks in high-throughput screening and de novo drug design,researchers in this area are turning again to natural products.Shikonin,which is isolated from Lithospermum erythrorhizon,has multifarious pharmacological properties including antibacterial activity.
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