Bayesian Hierarchical Models for Safety Analysis

来源 :泛华统计学会(icsa)2015年学术会议 | 被引量 : 0次 | 上传用户：wei616

【摘要】

：

Safety analysis plays a critical role in drug development.However,a large number of different types of AEs are routinely collected in clinical trials so that mu

【作者】

：

Cong Xu

【机构】

：

NovartisPharmaceuticals,China

【出处】

：

泛华统计学会(icsa)2015年学术会议

【发表日期】

：

2015年7期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

Safety analysis plays a critical role in drug development.However,a large number of different types of AEs are routinely collected in clinical trials so that multiplicity is a challenging problem.

其他文献

推动无机化学与化工学科交叉,培养创新人才,迎接新时代化学面临的机遇和挑战

　　提倡用无机化学和化工学科进行学科交叉研究方法，用多学科交叉研究方法研究无机化合物获得的创新理论，通过化工专业结合去实现产业化。多学科交叉方法迎接新时代当前人类正

会议

取向组装诱导可控合成多级结构功能介孔材料

多级结构功能介孔材料不仅具备介孔材料的独特性质,如高比表面积、孔道尺寸和孔容均一可控,而且具有无机功能纳米颗粒优异的光学、电学、磁学等特性.因此多级结构功能介孔材

会议

DIMENSIONAL CROSSOVER IN COORDINATION CHEMISTRY

　　Here,we demonstrate a bottom-up approach for the fabrication of well-defined dimensional-crossover nano-architectures with high tunability using metal ions

会议

Network optimization with devolution filtering in the high-dimensional data

Identification of the direct relationship between variables in the high-dimensional data remains challenging,since biological network always contains numerous i

会议

Comparative evaluation of Gene set analysis methods for differential expression gene set

　　Objective To compare the efficiency of four methods,namely significance analysis of function and expression(SAFE),Eforns Gene Set Analysis(Eforns GSA),Globa

会议

Gene setDifferent Expression Gene setCompute simulationInference

硒化合物干预阿尔茨海默症的作用机制研究

　　生物必需微量元素硒对维持中枢神经系统的正常功能具有重要作用,长期缺硒会引起包括阿尔茨海默症(AD)在内的多种脑疾病,越来越多的研究证明硒缺乏影响AD 病理过程中的诸

会议

Research on the imputation fusion methods of gene expression profiling with missing data

Background:Due to characteristic of massive amounts,complexity,noise and high dimension for gene expression data,especially the abundant missing value,which had

会议

Bayesian hierarchical models for prognostic prediction using large-scale molecular data

Large-scale molecular profiling data generated by high-throughput technologies have offered extraordinary opportunities to improve prognosis and prediction of c

会议

SRM method on multi-sources and continues inputting data

　　The public health data is often collected from multi-sources and in the form of continues inputting data,e.g.incidence of infectious diseases from data repo

会议

distribution of infectious diseaseSRM methodstates descriptionmulti-sourcesc

Bayesian Gaussian process for mean regression with varying residuals

In this talk,we consider Bayesian nonparametric regression with the residual errors to change flexibly with predictors.We specify the mean regression function w

会议

Bayesian Hierarchical Models for Safety Analysis

其他学术论文