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  5. MiR-19b reduces intestinal inflammation via down-regulation of colonic SOCS3 expression in Crohn

MiR-19b reduces intestinal inflammation via down-regulation of colonic SOCS3 expression in Crohn

来源 :The 14th Congress of Gastroenterology China(第十四届全国消化系病学术会议) | 被引量 : 0次 | 上传用户：bian123
【摘 要】
：
Background and aims The aim of our study was to investigate the contribution of SOCS3 expression-associated miRNA to modulate production of chemokine in intestinal epithelial cells and is associated w
【作 者】
：
X.O.Cheng X.F.Zhang Y.D.Zhang L.Lin R.H.Shi H.J.Zhang 
【机 构】
：
Department of Gastroenterology, First Affiliated Hospital of Nanjing Medical University, Nanjing, Ji
【出 处】
：
The 14th Congress of Gastroenterology China(第十四届全国消化系病学术会议)
【发表日期】
：
2014年5期
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Background and aims The aim of our study was to investigate the contribution of SOCS3 expression-associated miRNA to modulate production of chemokine in intestinal epithelial cells and is associated with the pathogenesis of Crohns Disease.Methods miRNA-SOCS3 pairs were predicted by bioinformatic approaches and alterations of these miRNA-SOCS3 pairs in CD patients were detected by quantitative real-time PCR (qRT-PCR).
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