125I粒子植入联合化疗治疗晚期非小细胞肺癌的临床研究

来源 :中华医学会第十四次全国内科学学术会议、第九届全国呼吸道感染学术大会、第五届全国抗感染药物合理应用论坛暨2013年北京-香 | 被引量 : 0次 | 上传用户:realno158
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目的 探讨CT引导下放射性粒子125 I植入联合化疗治疗晚期非小细胞肺癌(NSCLC)的近期疗效及并发症的发生情况.方法 术前经临床影像学及病理学检查确诊为ⅢB-Ⅳ期NSCLC患者70例,其中32例在CT引导下行放射性粒子125 I植入联合化疗治疗(研究组);38例行单纯化疗(对照组),化疗方案为DP方案(多西他赛+顺铂).治疗后6个月复查胸部CT测量肿瘤体积,按肿瘤病灶分类及疗效评价标准评定疗效;并随访观察两组患者的无进展生存时间(progression-free survival,PFS)及其毒副作用的发生情况.
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