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Summary of Background Data: An increasing interest in the potential benefits of cognitive motor exercise(CME) for stroke is recently observed, but the efficacy of CME for gait and balance is controversial.
Purpose: We performed a systematic review and meta-analysis of randomized controlled trials to estimate the effect of CME on gait and balance in patients with stroke.
Methods: We searched articles in Medline, Embase, the Cochrane Library, Web of Science, CINAHL,PEDro, and the China Biology Medicine disc from 1970 to July 2014.Only randomized controlled trials examining the effects of CME for patients with stroke were included, and no language restrictions were applied. Main outcome measures included gait and balance function.
Results: A total of I S studies composed of 395 participants met the inclusion criteria, and 13 studies of 363 participants were used as data sources for the meta-analysis. Pooling revealed that CME was superior to control group for gait speed [mean difference (MD;95％ CI)=0.19 m/s (0.06,0.31),P=0.003],stride length [MD (95% CI) =12.53 cm (4.07, 20.99),P=0.004],cadence [MD (95% CI)=10.44 steps/min (4.17,16.71),P=0.001],Center of pressure sway area [MD(95% CI)=-1.O5(-1.85，-0.26),P=0.01],Berg balance scale[MD(95% CI)=2.87(0.54,5.21),P=0.02]in the short term.
Conclusion: CME is effective for improving gait and balance function for stroke in the short term.However, only little evidence supports the assumption regarding CMEs long-term benefits.