【摘 要】
：
Aim:To identify gene mutations of potassium channels that contributed to the pathogenesis of atrial fibrillation.Method:Genomic DNA was extracted from the p
【机 构】
：
泸州医学院忠山校区心研所,泸州,646000
【出 处】
：
中国生理学会第24届全国会员代表大会暨生理学学术大会
论文部分内容阅读
Aim:To identify gene mutations of potassium channels that contributed to the pathogenesis of atrial fibrillation.Method:Genomic DNA was extracted from the peripheral blood of 124 patients with atrial fibrillation.The coding regions of genes including KCNE1 (minK),KCNE1L (KCNE5),KCNE2 (MiRP1),KCNE4 (MiRP3),KCNJ2 (Kir2.1) and KCNJ4 (Kir2.3) were amplified from the genomic DNA and sequenced with corresponding primers.
其他文献
Background- Local flow patterns determine the uneven distribution of atherosclerotic lesions.Sensing mechanical forces,membrane lipid rafts are crucial for
目的：利用大鼠血管钙化模型探讨硫化氢(Hydrogen sulfide,H2S)是否可通过抑制内质网应激(Endoplasmic reticuclum,ERS)而改善血管钙化.方法：钙化模型制备：180g-200g 雄性SD
摘要： 数学课堂提问是学生主体活动的过程，离开学生的主体学习活动，数学课堂教学的目标就无法真正实现，而课堂提问是促进学生主动学习的最有效的方法之一。实践表明，有效的问题，有利于调动全体学生投入自我探索，有利于师生间、生生间的情感沟通和信息交流，有利于思维的撞击和智慧火花的迸发，尤其有利于学生创造性思维和创造能力的培养。 关键词：小学数学；提问 一、课堂提问具有趣味性 在小学数学教学中，小学生
Hydrogen sulfide (H2S) plays an important role in cardiovascular system.The major mechanism of renal vascular hypertension consists of over-activation of re
As a member of the tissue KLK family,KLK8 has been detected in a variety of tissues and biological fluids.However,the role of KLK8 in the fundamental proces
Background: Autonomic dysfunction is implicated in prehypertension and previous studies demonstrated that therapies improving modulation sympathovagal balan
宫颈癌、胃癌的发病率高并难以治疗,在其肿瘤化疗过程中,抗癌药物在杀伤肿瘤细胞的同时,对正常免疫细胞也有杀伤作用,严重影响化疗的疗效。因此,急需寻找新型高效低毒的抗癌
目的：壬基苯酚(Nonylphenol,NP)是环境雌激素中具有代表性的一种。心脏表达丰富的雌激素受体,本实验研究了钙通道介导的环境雌激素壬基苯酚的心血管毒性作用及其机制。方
室旁核(PVN)在交感神经活动和血压调节中起重要作用。本研究探讨PVN 中松弛素-2(relaxin-2)在高血压发病中的作用与机制。实验采用13 周龄的WKY 大鼠和自发性高血压大鼠(