Histone-inspired biomimetic polymeric gene vehicles with excellent biocompatibility and enhanced tra

• 作 者: Peng-Fei Cui Lei Xing Hu-Lin Jiang
• 机 构: State Key Laboratory of Natural Medicines,Department of Pharmceutics,China Pharmaceutical University
• 出 处: 2016年中国药物制剂大会、中国药学会药剂专业委员会2016年学术年会、中国化学制药工业协会固体制剂专业委员会2016年
• 发表日期: 2016年4期

　　Limited delivery options have hindered the development of nucleic acids drugs in clinical practice.Inspired by the nature DNA compressing ability of histone,herein we synthesis polymeric carriers called PCAmHn designed to mimic histone mechanisms of gene delivery.