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Objectives To observe the safety and availability of anticoagulation of low-intensity warfarin anticoagulant therapy in AF patients with high stroke risk and high risk of bleeding applying CHA2DS2VASc stroke risk score and bleeding risk scoring HASBLED (CHA2DS2VASc ≥1 and HAS-BLED ≥3)by using the scoring system in the 2010 ESC Guideline.