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Background Inflammation participates in host defenses against infectious agents and injury,but it also contributes to the pathophysiology of many chronic diseases.In the last decade,a hypothesis was proposed to associate the pathogenesis of type 2 diabetes mellitus (T2DM) with a state of subclinical chronic inflammation,and the degree of subclinical chronic inflammation was reported to be similar between subjects with prediabetes mellitus (PreDM) and individuals with T2DM.