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Autotetraploid rice bears stronger biological heterosis than diploid rice,while its low seed setting rate has effects on wide utilization in rice breeding.Through studies in several successive years,some autotetraploid rice crosses with high seed setting rate were obtained.To investigate genetics of seed setting rate in autotetraploid rice,genetic effects of directional selection on seed setting rate and correlation between seed setting rate and agronomy traits were studied by analyzing the data of successive F1-F6 offspring,which were derived from autotetraploid hybrids Guangluai 4-4xxL202-4x with high seed setting rate.