A comparative study of EUS, CT, and MRCP to predict malignancy of branch-duct type intraductal papil

• 作 者: Wu Dong Guo Tao Wu Xi Yao Fang Yang Aiming Qian Jiaming
• 机 构: Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College,
• 出 处: 第十一届全国肠道疾病学术大会暨2015天津消化内镜年会
• 发表日期: 2016年8期
• 关键词: intraductal papillary mucinous neoplasm branch duct-intraductal papillary mucino

　　Background: Prediction of the malignancy of intraductal papillary mucinous neoplasm (IPMN)remains difficult,especially for the mixed type.Objective: The aim of this study was to evaluate the usefulness of EUS to predict malignancy for resection of branch duct-type (BD)-IPMN and to compare them with spiral CT and MRCP.Methods: A prospectively collected database of patients with resected BD-IPMN who receive EUS,CT and MRCP before the operation was analyzed to compare factors as predictors of malignancy.Results: Of 42 patients with BD-IPMN,14 were diagnosed as malignancy according to surgical pathology.The sensitivity (0.72) and specificity (0.75) of EUS were superior to those of CT (0.62 and 0.72) and MRCP (0.52 and 0.68).Multiple logistic regression analysis showed that main pancreatic duct dilatation greater than 5 mm (HR 5.56,95% CI 2.45 ~ 9.62;P < 0.001),mural nodules (HR 4.28,2.15 to 10.21;P < 0.001) and carbohydrate antigen 19-9 level above 37 units/ml (HR 3.02,1.25 to 10.90;P =0.001) were independent predictors of BD-IPMN malignancy.