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Objective:To evaluate mid-term (5-6year) clinical and radiographic outcomes associated with cementless acetabular components that had been inserted by a senior surgeon in cementless total hip arthroplasty (THA). The factors affecting postoperative effect are discussed. Methods:This study examined the mid-term (equal or more than 5 years) results of THA. A series of 109 patients (116 hips) who had undergone THA with cementless acetabulum in our hospital were available for follow-up in this study. All patients were evaluated both clinically (with use of the Harris hip score) and radiographically (with use of the most recent anteroposterior pelvic radiograph with the immediate postoperative radiograph as well as with any interim serial radiographs.). All evaluations were performed by an independent examiner who had not participated in the operation. Acetabular migration,bone changes around the implant, the polyethylene wear rate and direction of the acetabular polyethylene wear were measureed radiologically. Results:The mean Harris score was 44(range10-70) points before surgery, increased to 92.4(range80-100) points at latest follow-up. No acetabular component had been revised because of aseptic loosening, and no acetabular component had migrated. All the acetabulars were classified as stable on radiography. There were no revision of a fixed acetabular component because of pelvic osteolysis secondary to polyethylene wear. The mean linear wear rate was 0.15mm/yr .Conclusions:In terms of fixation, cementless acetabular components used in THA performed successfully in mid-term. Because polyethylene wear and osteolysis can not avoid ,radiographical followup for cementless acetabular components is very important.